
Dr Tan Kok Kuan
Men’s Health & Sexual Health Doctor
MBBS (S’pore), Cert. Men’s Health, Cert. Clinical Dermatology,Member, Academy for Men’s Health (Singapore)Member, Singapore Association for the Study of ObesityMember, International Society of Sexual Medicine

Persistently low testosterone levels can have adverse implications for men’s health over time. These changes may not always be noticeable at first, but leaving testosterone deficiency unaddressed can affect important bodily functions and contribute to longer-term health concerns.
However, a low testosterone reading alone does not necessarily indicate a condition requiring treatment. Testosterone levels can fluctuate, and determining whether a deficiency is present involves considering symptoms, repeat blood test results and possible underlying causes. This distinction is important when deciding whether medical intervention is necessary.
Understanding the potential effects of untreated low testosterone can help you recognise why identifying and addressing testosterone deficiency matters for your long-term health.
When testosterone remains below an appropriate level for a prolonged period, some of the clearest effects can involve the tissues that testosterone helps maintain. Bone health and muscle mass are particularly relevant, although the extent of these changes can differ considerably between individuals.
Testosterone helps maintain healthy bones in men. When a significant deficiency continues, bone mineral density may decline and contribute to osteopenia or osteoporosis.
This process may not cause noticeable symptoms at first. As a result, changes in bone strength may go unrecognised unless they are specifically assessed. Low testosterone does not mean that fractures will inevitably occur.
Age and existing bone health also influence fracture risk. Changes in bone density may develop without obvious symptoms, so bone health may form part of a broader assessment when testosterone deficiency persists.
Testosterone also supports lean muscle tissue. When levels remain low, some men may gradually lose muscle mass or find it harder to maintain their previous strength.
Over time, reduced muscle mass or strength may become more noticeable during everyday physical activities. Someone may find that tasks that once felt easy require more effort, particularly if the change develops gradually alongside other symptoms of testosterone deficiency.
Testosterone deficiency may affect sexual desire, erectile function and mood, particularly when it persists over time. These changes can vary between individuals and some symptoms may also be influenced by other health or lifestyle factors.
Testosterone plays an important role in regulating sexual desire. When testosterone levels are deficient, men may experience less interest in sexual activity, fewer spontaneous sexual thoughts or reduced responsiveness to sexual stimulation. Some may also notice fewer spontaneous or morning erections, although erectile difficulties can involve other factors, including blood circulation, psychological health and underlying medical conditions.
Persistent low testosterone may also be linked with changes in mood or motivation. These changes can develop gradually and may become more noticeable when they occur alongside other symptoms of testosterone deficiency. As mood can also be affected by other factors, a medical assessment can help determine whether low testosterone may be contributing.
Persistent low testosterone does not always cause one obvious problem. For some men, the main concern is that ongoing symptoms slowly begin to affect everyday life. The impact can vary depending on the cause and severity of the testosterone deficiency.
Men experiencing fatigue or reduced physical stamina may find it harder to sustain their usual level of activity. Exercise, work responsibilities and other daily tasks may require greater effort, particularly when tiredness occurs alongside reduced muscle strength.
However, fatigue is not specific to testosterone deficiency. Sleep disorders, psychological factors and other medical conditions can produce similar symptoms and should be considered during assessment.
Some men with testosterone deficiency report low mood, reduced motivation or difficulty concentrating. These changes can affect their sense of wellbeing, relationships and engagement in social activities, particularly when accompanied by persistent sexual or physical symptoms.
Although low testosterone has been associated with poorer quality of life in men with hypogonadism, these effects are not universal. Emotional and cognitive symptoms can have multiple causes, making it important to assess them in the context of a person’s overall health.
Taken together, persistent low testosterone deserves attention when changes are continuing or beginning to interfere with everyday life. Assessment can help distinguish testosterone deficiency from other possible causes and determine whether the hormone level itself needs to be addressed.

If you have ongoing symptoms or have previously been told that your testosterone level is low, a medical assessment can help establish whether testosterone deficiency is present and what may be contributing to it. A low result does not automatically mean that treatment is required, as symptoms and the underlying cause also need to be considered.
At Dr Tan Medical Center, Men’s Health & Sexual Health Doctor Dr Tan Kok Kuan brings more than 20 years of experience in men’s health and sexual health to the assessment and management of low testosterone. His approach emphasises understanding each patient’s concerns and overall health before recommending a course of action, helping men make informed decisions about their care rather than focusing solely on their testosterone levels.
If you have noticed persistent changes or would like to better understand your testosterone levels, book an appointment at our clinic for an individual assessment.
A single low testosterone result is generally insufficient to confirm the diagnosis. Testosterone levels fluctuate throughout the day and can be affected by factors such as illness and sleep. Diagnosis typically involves at least two separate morning blood tests, alongside an assessment of symptoms and other clinical findings.
Testosterone levels generally decline with age, but clinically significant testosterone deficiency should not simply be dismissed as a normal consequence of getting older. Men experiencing persistent symptoms alongside consistently low testosterone levels may require further evaluation to identify contributing conditions and determine whether treatment is warranted.
No. Treatment is not always necessary, and testosterone replacement therapy is not suitable for every man with low testosterone. Management may involve addressing contributing factors such as obesity, certain medications or underlying medical conditions. For men with confirmed symptomatic testosterone deficiency, treatment decisions also consider potential benefits, risks and future fertility plans.

Meet Our Doctor
Dr Tan Kok Kuan
Men’s Health & Sexual Health Doctor
MBBS (S’pore), Cert. Men’s Health, Cert. Clinical Dermatology,Member, Academy for Men’s Health (Singapore)Member, Singapore Association for the Study of ObesityMember, International Society of Sexual Medicine
Dr Tan Kok Kuan is an experienced doctor specialising in men's health, sexual health and medical weight loss. With over 20 years of clinical experience, he offers confidential and effective screening and treatment services. Notably, Dr Tan was one of the key authors of Singapore’s National HIV PrEP Guidelines and the national blueprint to end HIV transmission by 2030. Dr Tan frequently speaks at local and international conferences and has been featured in the media, where he helps raise public awareness around men’s health and sexual health.
“Every patient deserves our fullest attention.”
10 Sinaran Drive #09-30, Novena Medical Centre, Singapore 307506
Tel: (+65) 6513 0359 | WhatsApp: (+65) 9750 5037
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