Semaglutide, Ozempic, WeGovy & Rybelsus in Singapore

At Dr Tan Medical Center, our goal is to support patients in managing certain chronic conditions and lifestyle factors (such as diet and weight) effectively. Ozempic, Rybelsus, Wegovy, and Saxenda are medications that can sometimes help play a role in managing metabolic health, particularly for patients with type 2 diabetes, cardiovascular disease, and other related conditions.

What is Ozempic (Semaglutide)?

Ozempic is primarily used for managing type 2 diabetes. The active ingredient, semaglutide, works by helping to regulate blood sugar levels. Ozempic enhances insulin secretion when blood glucose levels are elevated and reduces glucagon secretion, which helps lower blood sugar levels between meals. This mechanism contributes to better overall glycemic control, reducing the risk of complications associated with diabetes, including heart disease and stroke.

Semaglutide is part of a family of medicines known as GLP-1 RAs (Glucagon Like Peptide Receptor Agonist). GLP-1 is a protein that is naturally produced by the gut in response to food. Semaglutide works by enhancing the amount of GLP-1 in the body, consequently giving the body back control over its energy intake and output.

What is Rybelsus (Oral Semaglutide)?

Rybelsus is an oral formulation of semaglutide and is primarily prescribed for the management of type 2 diabetes. Rybelsus works by regulating blood sugar levels through improved insulin sensitivity. It helps patients maintain stable blood glucose levels throughout the day by stimulating insulin release in response to elevated glucose and reducing glucagon secretion during periods of fasting.

By taking Rybelsus as prescribed, patients with type 2 diabetes can achieve better control over their blood sugar levels. This, in turn, helps reduce the risks associated with poorly managed diabetes; as well as other lifestyle effects.

What is Wegovy (Semaglutide)?

Wegovy is used in the management of obesity. It is generally indicated for patients with a BMI of 30 or higher, or 27 or higher with at least one weight-related comorbidity, such as type 2 diabetes, high blood pressure, or high cholesterol. Wegovy works by mimicking the action of a natural hormone in the body that regulates appetite, helping to reduce hunger and promote feelings of fullness.

In patients with metabolic conditions such as type 2 diabetes, Wegovy can play a role in improving overall health management. While the medication helps to support appetite regulation, its primary benefit lies in its ability to assist patients in managing conditions linked to obesity, such as cardiovascular disease and hypertension.

What is Saxenda (Liraglutide)?

Saxenda is generally indicated for the management of obesity in patients with a BMI of 30 or higher, or 27 or higher with at least one associated health condition such as type 2 diabetes or high blood pressure. The active ingredient in Saxenda, liraglutide, works by targeting the brain's appetite centers to promote feelings of fullness and reduce hunger.

For patients with obesity and metabolic conditions, Saxenda can complement their treatment plan by helping to manage their weight in conjunction with lifestyle changes such as diet and exercise. This helps to improve metabolic health and helps reduce the risks associated with obesity-related complications like cardiovascular disease and diabetes.